Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The experimental data of partition coefficient is obtained according to OECD Guideline no. 107.
A supporting value is predicted by the ACD/Labs’ ACD/PhysChem Suite.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

The experimental value of the logPow for 12-ketochenodeoxycholic acid is 2.97. Considering also the predicted log Pow value of 2.38 by ACD/Labs’ ACD/PhysChem Suite it can be concluded that the substance has a moderate partition coefficient. The values, however, should be evaluated considering the amphipathic nature of bile acids. It can be therefore supposed that, in a biphasic solution, 12-ketochenodeoxycholic acid will be mainly distributed at the interface of the two phases.