Quaternary ammonium compounds, di-C12-18-alkyldimethyl, chlorides

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Link to relevant study record(s)

Reference

Reference 1

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From February 16, 2007 to April 27, 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

GLP compliance:

yes (incl. QA statement)

Key result

Relative self-ignition temperature:

> 403 °C

Remarks on result:

other: at atm. press. of ca.1013.0 hPa

No self-ignition temperature was observed up to the maximum test temperature of 403 °C.

Conclusions:

Under the study conditions, no self-ignition temperature for the test substance was observed up to the maximum test temperature of 403°C.

Executive summary:

A study was conducted to determine the self-ignition temperature of test substance, DDAC (99.8% active) according to the EU Method A.16, in compliance with GLP. 8 cm³(2.7 g) of the test substance was placed in an oven under increasing temperature up to 400°C at a rate of 0.5°C/min. Purified active substance (obtained via lyophilation of aqueous solution) was used in the study. Under the study conditions, no self-ignition temperature for the test substance was observed up to the maximum test temperature of 403°C (Moller, 2007).

Reference 2

Endpoint:

relative self-ignition temperature (solids)

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Study period:

From February 16, 2007 to April 27, 2007

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

KL2 due to RA

Justification for type of information:

Refer to section 13 of IUCLID for details on the read-across justification. The study with the read across substance is considered sufficient to fulfil the information requirements as further explained in the provided endpoint summary.

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

GLP compliance:

yes (incl. QA statement)

Key result

Relative self-ignition temperature:

> 403 °C

Remarks on result:

other: at atm. press. of ca.1013.0 hPa

No self-ignition temperature was observed up to the maximum test temperature of 403 °C.

Conclusions:

Based on the results of the read across study, no self-ignition temperature for the test substance was considered up to the maximum test temperature of 403°C.

Executive summary:

A study was conducted to determine the self-ignition temperature of read across substance, DDAC (99.8% active) according to the EU Method A.16, in compliance with GLP. 8 cm³(2.7 g) of the read across substance was placed in an oven under increasing temperature up to 400°C at a rate of 0.5°C/min. Purified active substance (obtained via lyophilation of aqueous solution) was used in the study. Under the study conditions, no self-ignition temperature for the read across substance was observed up to the maximum test temperature of 403°C (Moller, 2007). Based on the results of the read across study, no self-ignition is expected for the test substance up to 403°C.

Description of key information

The self-ignition temperature of the read across substance, DDAC, was determined according to EU Method A.16 (Moller, 2007).   

Additional information

No self-ignition up to 403°C