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EC number: 268-608-0 | CAS number: 68131-04-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from October 18, 2007 to November, 10, 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- yes
- Remarks:
- stock solution was prepared in water pre-saturated with n-octanol
- Principles of method if other than guideline:
- - Short description of test conditions: A stock solution of the test substance should be prepared in n-octanol pre-saturated with water. Because of low solubility of the test substance in this medium, the stock solution was prepared in water pre-saturated with n-octanol. This deviation has no effect on the determination of log Pow of the test substance.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- photometric method
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. -2.08
- Temp.:
- 23 °C
- pH:
- 9.5
- Details on results:
- Standard extended uncertainty 0.44.
- Conclusions:
- Partition coefficient (log P) of the test substance - Humic acids, sodium salts - determined by shake-flask method is:
log Pow = -2.08 ± 0.44 (pH = 9.5, 23ºC)
The partition coefficient shows some suggestion of concentration dependency. - Executive summary:
The partition coefficient of the test substance was determined. The shake-flask method was used.
The test was performed according to the Method A.8, Partition coefficient, Directive 92/69/EEC, Published in OJ No L 383A, 1992.
Reference
Description of key information
hod A.8, Partition coefficient, Directive 92/69/EEC, Published in OJ No L 383 A, 1992.
GLP study.is:
log Pow = -2.08 ± 0.44 (pH = 9.5, 23ºC)
The partition coefficient of the test substance was determined. The shake-flask method was used.
The test was performed according to the Method A.8, Partition coefficient, Directive 92/69/EEC, Published in OJ No L 383A, 1992.
Partition coefficient (log P) of the test substance - Humic acids, sodium salts - determined by shake-flask method is: log Pow = -2.08 ± 0.44 (pH = 9.5, 23ºC)
The partition coefficient shows some suggestion of concentration dependency.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.08
- at the temperature of:
- 20 °C
Additional information
The partition coefficient of the test substance was determined. The shake-flask method was used.
The test was performed according to the Method A.8, Partition coefficient, Directive 92/69/EEC, Published in OJ No L 383A, 1992.
Partition coefficient (log P) of the test substance - Humic acids, sodium salts - determined by shake-flask method is:
log Pow = -2.08 ± 0.44 (pH = 9.5, 23ºC)
The partition coefficient shows some suggestion of concentration dependency.
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