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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From March 2018 to May 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
July 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
May 2008
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: D653 22_02_2018
- Expiration date of the lot/batch: Feburary 2023
- Purity test date: 2018/02/27
Key result
Water solubility:
0.124 g/L
Temp.:
20 °C
pH:
7.5
Details on results:
No pH adjustement was performed in the main test.

In the preliminary test results,the test item was still not completely dissolved in 100 ml of water

In the main test, the concentrations measured in the two last vessels do not differ by more than 15% therefore, the test was considered as valid.

Sample (stirring time)  Solubility (g/L)  Average Solubility per sample (g/L)  pH
 One Day

0.111

0.110

0.110

0.110  7.5
Two days

0.134

0.134

0.134

0.134  7.5 

Three days

 0.129

0.128

0.128

0.128  7.5 
Conclusions:
The test item water solubility at 20°C and pH 7.5 is 0.124 g/L.The test item is considered slightly soluble in water
Executive summary:

The test item water solubility was determined with the flask method according to recognised guidelines. No deviation from the guidelines was observed during the study.

A preliminary test was performed in order to estimate the water solubility of the test item.

In the main test, the test iem water solubility is 0.124 g/l at 20°C and pH 7.5. The test item is considered slightly soluble in water

Endpoint:
water solubility
Type of information:
not specified
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
No details on method are given, however the data source is considered reliable.
Principles of method if other than guideline:
no data
GLP compliance:
no
Type of method:
other: no data
Remarks on result:
other: Partly soluble
Conclusions:
Partly soluble
Executive summary:

1,2-dichloro-1,1,2-trifluoro-2-(trifluoromethoxy)ethane is reported to be partly soluble in water.

Description of key information

The test item water solubility was experimentally determined in a key study performed under GLP according to OECD guideline No. 105.

The results obtained in the key study were confirmed by a supporting study.

Key value for chemical safety assessment

Water solubility:
124 mg/L
at the temperature of:
20 °C

Additional information

Based on its water solubility value, the test item is considered partly soluble in water.