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Registration Dossier
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EC number: 219-094-1 | CAS number: 2356-53-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- June 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- ebulliometer
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Appearance: Liquid
- Source and lot/batch: D653 22_02_2018
- Purity: 99.9%
- Expiration date of the lot/batch: February 2023
- Purity test date: 2018/02/27 - Key result
- Boiling pt.:
- 40.7 °C
- Atm. press.:
- 1 013 hPa
- Decomposition:
- no
- Conclusions:
- The boiling point of the test item was determined to be 40.7°C at 1013 hPa
- Executive summary:
This test was performed to determine the boiling temperature of the test item. It was conducted in accordance with the procedure described in EU Regulation (EC) 440/2008, Annex Part A test A.2 and OECD Test Guideline 103.
The boiling point of the test item was determined to be 40.7°C at 1013 hPa (mean of 2 runs).
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- No details on method are given, however the data source is considered reliable.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
- Type of method:
- other: no data
- Boiling pt.:
- 41 °C
- Remarks on result:
- other: BP = 41 °C
- Conclusions:
- 1,2-dichloro-1,1,2-trifluoro-2-(trifluoromethoxy)ethane has a boiling point of 41°C.
- Executive summary:
1,2-dichloro-1,1,2-trifluoro-2-(trifluoromethoxy)ethane has a boiling point of 41 °C.
Referenceopen allclose all
Two runs were performed.
- Run 1:
Number Mass of sample Used : 0.229 g
Boiling Temperature: 40.6 °C
- Run 2:
Number Mass of sample Used : 0.214 g
Boiling Temperature: 40.7°C
Description of key information
The boiling point of the test item was investigated in a GLP-compliant study performed in accordance with EC A.2 method and OECD Guideline No. 103.
The boiling point of the test item was determined to be 40.7°C at 1013 hPa (mean of 2 runs).
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 40.7 °C
Additional information
The boiling point of the test item was investigated in one GLP-compliant study performed in accordance with standard method, without deviations. The study is considered as reliable (Klimisch 1) and is selected as a key study for the endpoint.
A consitent value of 41°C was reported on Safety Data Sheet of the registrant company. No details on the measurement are available. The value is reported as supporting data.
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