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Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Additional information

No data available.


Short description of key information:
According to Regulation (EC) No 1907/2006, Annex VIII 8.7.1. column 2, a screening study for reproductive/developmental toxicity is not required if a pre-natal developmental toxicity study (Annex IX, 8.7.2) or a two-generation reproductive toxicity study (Annex IX, Section 8.7.3) is available.
A GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiatedat a contract research organisation. Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).

Justification for selection of Effect on fertility via oral route:
According to Regulation (EC) No 1907/2006, Annex VIII 8.7.1. column 2, a screening study for reproductive/developmental toxicity is not required if a pre-natal developmental toxicity study (Annex IX, 8.7.2) or a two-generation reproductive toxicity study (Annex IX, Section 8.7.3) is available. A GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiated at a contract research organisation . Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).

Effects on developmental toxicity

Description of key information
There are no data available to assess the developmental toxicity of [3-(triethoxysilyl)propyl]urea. However, a GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiated at a contract research organisation . Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).
Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available (further information necessary)
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available
Additional information

No data available.


Justification for selection of Effect on developmental toxicity: via oral route:
There are no data available to assess the developmental toxicity of [3-(triethoxysilyl)propyl]urea. However, a GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiated at a contract research organisation. Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).

Justification for classification or non-classification

No data available.

Additional information

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