Registration Dossier
Registration Dossier
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EC number: 245-876-7 | CAS number: 23779-32-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Additional information
No data available.
Short description of key information:
According to Regulation (EC) No 1907/2006, Annex VIII 8.7.1. column 2, a screening study for reproductive/developmental toxicity is not required if a pre-natal developmental toxicity study (Annex IX, 8.7.2) or a two-generation reproductive toxicity study (Annex IX, Section 8.7.3) is available.
A GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiatedat a contract research organisation. Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).
Justification for selection of Effect on fertility via oral route:
According to Regulation (EC) No 1907/2006, Annex VIII 8.7.1. column 2, a screening study for reproductive/developmental toxicity is not required if a pre-natal developmental toxicity study (Annex IX, 8.7.2) or a two-generation reproductive toxicity study (Annex IX, Section 8.7.3) is available. A GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiated at a contract research organisation . Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).
Effects on developmental toxicity
Description of key information
There are no data available to assess the developmental toxicity of [3-(triethoxysilyl)propyl]urea. However, a GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiated at a contract research organisation . Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available (further information necessary)
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Additional information
No data available.
Justification for selection of Effect on developmental toxicity: via oral route:
There are no data available to assess the developmental toxicity of [3-(triethoxysilyl)propyl]urea. However, a GLP-compliant prenatal developmental toxicity study (OECD 414) with the structural analogue substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS 116912-64-2) has been initiated at a contract research organisation. Once the data is available it will be read-across to [3-(triethoxysilyl)propyl]urea (CAS 23779-32-0).
Justification for classification or non-classification
No data available.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
