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EC number: 270-096-9 | CAS number: 68411-04-1
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Version / remarks:
- 1981
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: sieving followed by scanning electron microscopy
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- 5.3 µm
- No.:
- #1
- Size:
- < 4 µm
- Distribution:
- 0.32 %
- Remarks on result:
- other: spherical volume
- No.:
- #2
- Size:
- >= 4 - < 10 µm
- Distribution:
- 6.42 %
- Remarks on result:
- other: spherical volume
- No.:
- #3
- Size:
- >= 10 - < 100 µm
- Distribution:
- 93.26 %
- Remarks on result:
- other: spherical volume
- No.:
- #4
- Size:
- > 100 µm
- Distribution:
- 0 %
- Remarks on result:
- other: spherical volume
- Conclusions:
- The MMAD (Mass Median Aerodynamic Diameter < 100μm) of the test item has a value of 5.30 μm as spherical particles.
- Executive summary:
The sample is fractionated by a 100 μm sieve and tested by scanning electron microscopy (SEM). The fraction < 100 μm is gushed to carbon pads and sputtered with gold.
The particle classification (mean diameter): 0.4-0.5, 0.5-1.0, 1-2, 2-3, 3-5 and 5-100 μm, additional <0.4 and >100μm is reported.
The mass fraction is calculated for spherical and cubical volume in classes of particle diameter <4 μm, 4-10 μm, 10-100 μm and > 100 μm.
Result: Sieve Fraction
weighted sample: 1.5459 g
weight fraction <100 μm: 0.0331 g
mass fraction <100 μm: 2.14 %
The MMAD (Mass Median Aerodynamic Diameter < 100μm) of the test item has a value of 5.30 μm as spherical particles.
Reference
Accounting based on total sample weight
| Particle size (µm) | Spherical volume (%) | |
| Mass fraction | >100 | 97.86 |
| Sieve fraction | >100 | 0.00 |
| Total (>100µm) | 97.86 | |
| Sieve fraction | 10 -100 (inhalable) | 2.00 |
| Sieve fraction | 4 -10 (thoraic) | 0.14 |
| Sieve fraction | <4 (respirable) | 0.01 |
Description of key information
The sample is fractionated by a 100 μm sieve and tested by scanning electron microscopy (SEM). The fraction < 100 μm is gushed to carbon pads and sputtered with gold.
The particle classification (mean diameter): 0.4-0.5, 0.5-1.0, 1-2, 2-3, 3-5 and 5-100 μm, additional <0.4 and >100μm is reported.
The mass fraction is calculated for spherical and cubical volume in classes of particle diameter <4 μm, 4-10 μm, 10-100 μm and > 100 μm.
Result: Sieve Fraction
weighted sample: 1.5459 g
weight fraction <100 μm: 0.0331 g
mass fraction <100 μm: 2.14 %
The MMAD (Mass Median Aerodynamic Diameter < 100μm) of the test item has a value of 5.30 μm as spherical particles.
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