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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
Version / remarks:
1981
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
other: sieving followed by scanning electron microscopy
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
5.3 µm
No.:
#1
Size:
< 4 µm
Distribution:
0.32 %
Remarks on result:
other: spherical volume
No.:
#2
Size:
>= 4 - < 10 µm
Distribution:
6.42 %
Remarks on result:
other: spherical volume
No.:
#3
Size:
>= 10 - < 100 µm
Distribution:
93.26 %
Remarks on result:
other: spherical volume
No.:
#4
Size:
> 100 µm
Distribution:
0 %
Remarks on result:
other: spherical volume

Accounting based on total sample weight

   Particle size (µm)  Spherical volume (%)
 Mass fraction >100  97.86 
 Sieve fraction  >100 0.00 
 Total (>100µm)   97.86 
  Sieve fraction 10 -100 (inhalable)  2.00 
  Sieve fraction 4 -10 (thoraic)  0.14 
  Sieve fraction <4 (respirable)  0.01 
Conclusions:
The MMAD (Mass Median Aerodynamic Diameter < 100μm) of the test item has a value of 5.30 μm as spherical particles.
Executive summary:

The sample is fractionated by a 100 μm sieve and tested by scanning electron microscopy (SEM). The fraction < 100 μm is gushed to carbon pads and sputtered with gold.

The particle classification (mean diameter): 0.4-0.5, 0.5-1.0, 1-2, 2-3, 3-5 and 5-100 μm, additional <0.4 and >100μm is reported.

The mass fraction is calculated for spherical and cubical volume in classes of particle diameter <4 μm, 4-10 μm, 10-100 μm and > 100 μm.

Result: Sieve Fraction

weighted sample: 1.5459 g

weight fraction <100 μm: 0.0331 g

mass fraction <100 μm: 2.14 %

The MMAD (Mass Median Aerodynamic Diameter < 100μm) of the test item has a value of 5.30 μm as spherical particles.

Description of key information

The sample is fractionated by a 100 μm sieve and tested by scanning electron microscopy (SEM). The fraction < 100 μm is gushed to carbon pads and sputtered with gold.

The particle classification (mean diameter): 0.4-0.5, 0.5-1.0, 1-2, 2-3, 3-5 and 5-100 μm, additional <0.4 and >100μm is reported.

The mass fraction is calculated for spherical and cubical volume in classes of particle diameter <4 μm, 4-10 μm, 10-100 μm and > 100 μm.

Result: Sieve Fraction

weighted sample: 1.5459 g

weight fraction <100 μm: 0.0331 g

mass fraction <100 μm: 2.14 %

The MMAD (Mass Median Aerodynamic Diameter < 100μm) of the test item has a value of 5.30 μm as spherical particles.

Additional information