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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: ETAD Analytical exptert group
Version / remarks:
method for substances with very low solubility in both, water and n-octanol
Principles of method if other than guideline:
Calculation of log Pow from solubility in n-octanol (see section 4.9) and in water (see section 4.8).
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Dimethyl 5-[[1-[[(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)amino]carbonyl]-2-oxopropyl]azoterephthalate
EC Number:
249-955-7
EC Name:
Dimethyl 5-[[1-[[(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)amino]carbonyl]-2-oxopropyl]azoterephthalate
Cas Number:
29920-31-8
Molecular formula:
C21H19N5O7
IUPAC Name:
dimethyl 5-({2-oxo-1-[(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)carbamoyl]propyl}diazenyl)isophthalate

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
1.26
Temp.:
22 °C
pH:
ca. 7
Type:
log Pow
Partition coefficient:
0.1
Temp.:
22 °C
pH:
ca. 7

Any other information on results incl. tables

The n-octanol and the water solubility were both determined at 22 -23 °C and with the same test substance.

Calculation:

log Kow = logP = log (c(n-octanol)/c(water))

(c: individual solubilities; see below).

n-octanol sollubility: 240 µg/L

water solubility: 190 µg/L

pow: 1.26

log pow: 0.10

Applicant's summary and conclusion

Conclusions:
The calculated log Pow of the test substance is 0.10.

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