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Toxicological information

Carcinogenicity

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Description of key information

no oncogenic potential in rats
no oncogenic potential in mice

Key value for chemical safety assessment

Additional information

There was no evidence of any oncogenic effect of the test substance ( 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid: racemate) on rats and mice, when administered in the diet (for the typical life-span of the animals). The maximum dose administered was 3.0 mg/kg bw/day of the racemate.

Justification for classification or non-classification

There was no evidence of any oncogenic effect in the chronic/carcinogenicity studies (rat, mouse). As a result the substance does not meet the criteria for classification (carcinogenic substances) under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC, Annex VI, 4.2.1.

There was no evidence of any oncogenic effect in the chronic/carcinogenicity studies (rat, mouse). As a result the substance does not meet the criteria for classification (carcinogenicity) under Regulation (EC) 1272/2008, Annex I, Part 3, 3.6.2.