Registration Dossier
Registration Dossier
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EC number: 617-435-2 | CAS number: 83066-88-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only very little information is available. The information is based on an internal memorandum with a short summary of the results of a study report. The full study report is not available.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 981
Materials and methods
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- (RS)-2-[4-(5-Trifluoromethyl-2-pyridyloxy)phenoxy]propionic
- EC Number:
- 614-949-9
- Cas Number:
- 69335-91-7
- Molecular formula:
- C15H12F3NO4
- IUPAC Name:
- (RS)-2-[4-(5-Trifluoromethyl-2-pyridyloxy)phenoxy]propionic
- Reference substance name:
- 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid
- IUPAC Name:
- 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid
- Details on test material:
- The test substance is the racemate 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid (CAS# 69335-91-7). It is a 1:1 mixture of the two enantiomers (2R)-2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid (CAS# 83066-88-0; the substance defined in section 1) and (2S)-2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid (CAS# 95977-30-3).
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 5 000 mg/kg bw
- Based on:
- other: test substance (racemate)
- Other findings:
- A slight irritant effect was observed during the course of the experiment.
Any other information on results incl. tables
Full information as given in the memorandum:
Acute dermal LD50 (rats) 5000 mg/kg
A slight irritant effect was observed during the course of the experiment.
Applicant's summary and conclusion
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