Registration Dossier
Registration Dossier
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EC number: 228-391-5 | CAS number: 6258-06-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Remarks:
- other: in silico
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: The skin irritation module has not been validated.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
- Principles of method if other than guideline:
- Profiler based on the BfR rule base for waiving EU C&L for skin irritants (R34, R35, R38) based on physico-chemical properties.
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- The substance fulfills two criteria for being non irritating (lipid solubility < 0.01 g/kg, MP > 200°C) and two criteria for being an irritant (containing an aromatic amine and a ketone).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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