Registration Dossier
Registration Dossier
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EC number: 281-897-8 | CAS number: 84057-80-7
Endpoint summary
Administrative data
Description of key information
Additional information
Read-across approach
In the assessment of the environmental fate, ecotoxicity and toxicity of zirconium propionate (CAS: 84057-80-7), a read-across approach from data for the metal (zirconium) and the organic anion (propionate) is followed. This read-across strategy is based on the observation that upon dissolution in aqueous media, zirconium propionate dissociates and only is present in its dissociated form, i.e., as zirconium and propionate ions. Data on the environmental fate, ecotoxicity and toxicity for both transformation products (zirconium and propionate) together can therefore be combined in an additive approach to predict the corresponding properties of zirconium propionate.
A detailed justification for the read-across approach is added as a separate document in section 13 of IUCLID.
Upon dissolution and dissociation of zirconium salt propionate into zirconium cations and propionate anions, both ions will each show the proper (bio)degradation, bioaccumulation and partitioning behaviour in the environment, as reported for the corresponding ion. The environmental fate and behaviour for zirconium and propionate is predicted to be clearly different from each other, resulting in a different relative distribution over the environmental compartments (water, air, sediment and soil). Because the relative exposure to both constituent ions in the different environmental compartments is hence predicted to be different from the original composition of zirconium propionate, data for the ecotoxicological properties of this substance tested as such are considered less relevant for its effects and risk assessment and a read-across approach from data for both the zirconium and propionate ions is preferred. The dose additivity approach is used to predict the ecotoxicological effects of zirconium propionate based on the data for the individual transformation products (zirconium and propionate ions).
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