Registration Dossier
Registration Dossier
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EC number: 219-460-0 | CAS number: 2439-35-2
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: OECD publication
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- OECD
- Year:
- 2 003
- Bibliographic source:
- SIDS Initial Assessment Report (2-dimethylaminoethyl acrylate)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 406 (Skin Sensitisation)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of study:
- guinea pig maximisation test
Test material
- Reference substance name:
- 2-(dimethylamino)ethyl acrylate
- EC Number:
- 219-460-0
- EC Name:
- 2-(dimethylamino)ethyl acrylate
- Cas Number:
- 2439-35-2
- Molecular formula:
- C7H13NO2
- IUPAC Name:
- 2-(dimethylamino)ethyl prop-2-enoate
Constituent 1
Results and discussion
In vivo (non-LLNA)
Results
- Reading:
- 1st reading
- Hours after challenge:
- 24
- Group:
- test chemical
- Dose level:
- 5%
- No. with + reactions:
- 12
- Total no. in group:
- 19
- Remarks on result:
- other: Reading: 1st reading. . Hours after challenge: 24.0. Group: test group. Dose level: 5%. No with. + reactions: 12.0. Total no. in groups: 19.0.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
