Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-007-1 | CAS number: 7783-54-2
Neurotoxicity
Administrative data
Description of key information
Key value for chemical safety assessment
Effect on neurotoxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Effect on neurotoxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Effect on neurotoxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for selection of effect on neurotoxicity via oral route endpoint:
As nitrogen trifluoride is a gas, the oral route of exposure is not relevant
Justification for selection of effect on neurotoxicity via inhalation route endpoint:
No regulatory guideline studies on the neurotoxicity of NF3 have been undertaken. In the 90-day repeat dose inhalation studies in the rat (section 5.6.1.2) there were no behavioural observations which might suggest an effect of NF3 on the nervous system and there were no histopathological changes in the CNS.
Justification for selection of effect on neurotoxicity via dermal route endpoint:
As nitrogen trifluoride is a gas, the dermal route of exposure is not relevant
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
