Registration Dossier
Registration Dossier
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EC number: 947-119-2 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
DNNSA did not induce mutations in the Ames test and for BaDNNSA the chromosome aberration test and the mouse lymphoma test were negative. It is not expected that the barium cation will be of influence on the outcome of the testing. Therefore the tests on the salt will be used in a read-across approach.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
see read-across rationale in section 13
Justification for classification or non-classification
The test material, DNNSA and its Barium salt were negative in three in vitro genetic toxicity tests (Ames test, mouse lymphoma cell mutation assay and chromosome aberration test in human lymphocytes) and thus is not classified for genetic toxicity according to CLP (Regulation EC No 1272/2008) or DSD (Directive 67/548/EEC).
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