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EC number: 232-167-2 | CAS number: 7789-45-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on zinc (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification.zinc concentrations in test however not measured.
- Qualifier:
- according to guideline
- Guideline:
- other: American Society for testing matrials 1988: Standard practice for conducting acute toxicity tests with fishes, macroinvertebrates and amphibians, ASTM, E-729-88, Philadelphia
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Details on sampling:
- no data
- Vehicle:
- no
- Details on test solutions:
- standard reconstituted soft water (EPA 1975)
- Test organisms (species):
- other: Thymallus arcticus
- Details on test organisms:
- organisms from different origin were tested: they were from a) Clear state hatchery, Clear, Alaska, US (= code AC), and from Flathead lake salmon state hatchery, Somers, montana, US (code MT)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Hardness:
- 41 mg CaCO3/l
- Test temperature:
- 12 +/-1°C
- pH:
- 7.1-8.0
- Nominal and measured concentrations:
- no details given, nominal concentrations reported
- Details on test conditions:
- different life stages were tested
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 315 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I.: 234-424; test on "swim-up fry", origin AC
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 142 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95%C.I.114-178; test on 7-8w old juveniles, 0.2g, code AC
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 112 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95%C.I. 83-150; test on 7-8w old juveniles, 0.34g, code AC
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1 580 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95%C.I. 900-2770; test on alevins; code MT
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 166 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I. 127-217; test on 5-6w old juveniles, 0,97 g, code MT
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 2 920 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95%C.I. 2510-3400; test on alevins; code MT
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 168 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95%C.I. 143-197; test on 7-11w old juveniles, 0.97g, code MT
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 168 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I. 96-295; test on 7-11w old juveniles, 1.85g, code MT
- Reported statistics and error estimates:
- The method of Litchfield and Wilcoxon was used to calculate the LC50 values and 95%C.I.
signnificant differences between LC50 values were determined by the standard error of the differences as described by Sprague and Fogels 1977. - Validity criteria fulfilled:
- yes
- Conclusions:
- Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity.
- Executive summary:
Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on zinc (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification. LC50 values: see “results” section.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on zinc (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification.zinc concentrations in test however not measured.
- Qualifier:
- according to guideline
- Guideline:
- other: American Society for testing matrials 1988: Standard practice for conducting acute toxicity tests with fishes, macroinvertebrates and amphibians, ASTM, E-729-88, Philadelphia
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Details on sampling:
- no data
- Vehicle:
- no
- Details on test solutions:
- standard reconstituted soft water (EPA 1975)
- Test organisms (species):
- Oncorhynchus kisutch
- Details on test organisms:
- organisms from different origin were tested: they were from a) Clear state hatchery, Clear, Alaska, US (= code AK), and from Puyallup Salmon hatchery, Orting, Washington, US (code WA)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Hardness:
- 41 mg CaCO3/l
- Test temperature:
- 12 +/-1°C
- pH:
- 7.1-8.0
- Nominal and measured concentrations:
- no details given, nominal concentrations reported
- Details on test conditions:
- different life stages were tested
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 820 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I.: 610-1130; test on7-8w old juveniles, 0.47g, origin AK
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1 810 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I.: 1340-2450; test on7-8w old juveniles, 0.63g, origin AK
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1 650 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I.: 1050-2600; test on7-8w old juveniles,0.94g, origin AK
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 727 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I.: 507-1042; test on alevins, origin WA
- Reported statistics and error estimates:
- The method of Litchfield and Wilcoxon was used to calculate the LC50 values and 95%C.I.
signnificant differences between LC50 values were determined by the standard error of the differences as described by Sprague and Fogels 1977. - Validity criteria fulfilled:
- yes
- Conclusions:
- Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity.
- Executive summary:
Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on zinc (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification. LC50 values: see “results” section.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on zinc (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification.zinc concentrations in test however not measured.
- Qualifier:
- according to guideline
- Guideline:
- other: American Society for testing materials 1988: Standard practice for conducting acute toxicity tests with fishes, macroinvertebrates and amphibians, ASTM, E-729-88, Philadelphia
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Details on sampling:
- no data
- Vehicle:
- no
- Details on test solutions:
- standard reconstituted soft water (EPA 1975)
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- organisms from Ennis national fish hatchery Ennis, Montana (code: MT)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Hardness:
- 41 mg CaCO3/l
- Test temperature:
- 12 +/-1°C
- pH:
- 7.1-8.0
- Nominal and measured concentrations:
- no details given, nominal concentrations reported
- Details on test conditions:
- different life stages were tested
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 2 170 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% C.I.: 1850-2550; test on alevins, origin code MT
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 169 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95%C.I. 118-243; test on 7-10w old juveniles, 0.6g, code MT
- Reported statistics and error estimates:
- The method of Litchfield and Wilcoxon was used to calculate the LC50 values and 95%C.I.
signnificant differences between LC50 values were determined by the standard error of the differences as described by Sprague and Fogels 1977. - Validity criteria fulfilled:
- yes
- Conclusions:
- Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity.
- Executive summary:
Tests done according to standard protocol. Good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on zinc (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification. LC50 values: see “results” section.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1929
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data from HSDB database. Peer reviewed.
- Guideline:
- other: Not specified
- Principles of method if other than guideline:
- Conditions of bioassay not specified
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- No data
- Analytical monitoring:
- not specified
- Details on sampling:
- No data
- Vehicle:
- not specified
- Details on test solutions:
- No data
- Test organisms (species):
- Oncorhynchus kisutch
- Details on test organisms:
- Oncorhynchus kisutch (coho salmon)
- Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 96 h
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 286 µg/L
- Basis for effect:
- mortality (fish)
- Details on results:
- No further information
- Results with reference substance (positive control):
- No data
- Reported statistics and error estimates:
- No data
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In an experimental study where the toxicity of the substance copper dibromide on the coho salmon Oncorhynchus kisutch was assessed, the 96h-LC50 was determined to be 286 ug/L.
- Executive summary:
In an experimental study where the toxicity of the substance copper dibromide on the coho salmon Oncorhynchus kisutch was assessed, the 96h-LC50 was determined to be 286 ug/L.
Referenceopen allclose all
Description of key information
In an experimental study where the toxicity of the substance copper dibromide on the coho salmon Oncorhynchus kisutch was assessed, the 96h-LC50 was determined to be 286 ug/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 286 µg/L
Additional information
Supporting studies on an analogue substance having the same chemical structure (geometry) were added and gave 96h-LC50 between 166 and 2920 ug/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.