Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-924-9 | CAS number: 89-62-3
Endpoint summary
Administrative data
Description of key information
Additional information
Short term toxicity to fish
Based on the weight of evidence approach, the lethal concentration (LC50) value of 2-nitro-p-toluidine in various species of fish was found to range between 5 to 10 mg/L., with one study indicating an LC50 value of 11.1 mg/L. Thus, it is concluded that the chemical 2-nitro-p-toluidine shall exhibit aquatic toxicity to fish in the chronic category 2. The majority LC50 value of 5 mg/L has been considered for the chemical safety assessment.
Long term toxicity to fish
Long term toxicity (14 d) of 2-nitro-p-toluidine to fish was estimated to be LC50 = 3.989 mg/L.
Short term toxicity to aquatic invertebrate
The effective concentration (EC50) value of 2-nitro-p-toluidinein aquatic invertebrate (Daphnia Magna) in a 48 hr study based on mortality was estimated to be 1.111 mg/L. Thus, it is concluded that the chemical 2-nitro-p-toluidine shall exhibit aquatic toxicity to aquaitc invertebrate (Daphnia) in the chronic category 2.
Long term toxicity to aquatic invertebrate
Long term toxicity (96h) value of 2-nitro-p-toluidine to Chlorella pyrenoidosa was estimated to be EC50 equal to 4.995923 mg/L.
Toxicity to aquatic algae and cyanobacteria
The effective concentration (EC50) value of 2-nitro-p-toluidine in green algae in a 96 hr study on growth effect was estimated to be 6.326 mg/L. Thus considering only the value from CLP Criteria for aquatic classification of the substance , it is concluded that 2-nitro-p-toluidine could exhibit short term toxicity to green algae in the chronic 2 classification category.
Toxicity to micro-organisms
The inhibition growth concentration (IGC50) value of 2-nitro-p-toluidine in microorganism (Tetrahymena pyriformis) in a 60 hr study on the basis of growth inhibition effect was estimated to be 67.2 mg/L
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
