Registration Dossier
Registration Dossier
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EC number: 231-212-3 | CAS number: 7447-41-8
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic degradation / hydrolysis
The performance of a test for hydrolysis as function of pH is scientifically unjustified. The study need not to be conducted as lithium chloride completely dissociates in water forming lithium cation and and the corresponding chloride anion.
Biotic degradation
Biodegradation in water: screening test, Biodegradation in water and sediment, Biodegradation in soil
In accordance with column 2 of REACH Regulation 1907/2006/EC Annex VII section 9.2.1.1, a biodegradation test does not need to be conducted as the test substance lithium chloride is an inorganic substance. Furthermore according to REACH Annex X, Section 9.2, Column 2, further biotic degradation testing shall be proposed, if the chemical safety assessment according to Annex I indicates the need to investigate further degradation.
The CSA does not indicate any need to further assess degradation. Risk assessment was already performed assuming worst case conditions including “no biodegradation”. All risks are adequately controlled. Thus, any further information that would lead to the conclusion that the registered substance is not biodegradable would not influence the chemical safety assessment. Please refer to the attached CSR in IUCLID section 13 for further information.
Bioaccumulation in aquatic/ sediment
In accordance with column 2 of REACH Regulation 1907/2006/EC Annex IX section 9.3.2, the Bioconcentration Factor, BCF does not need to be conducted as lithium chloride is expected to have a low potential for bioaccumulation (log Kow expected in the negative range (consequently << 3)). The theoretical, calculated (EPIWIN) log Pow is -0.46, i.e. in the negative range, as expected for an inorganic salt. Therefore, no testing on bioaccumulation is needed. The lack of bioaccumulation is also supported by kinetic studies in humans, revealing a fast and complete excretion of absorbed lithium.
Adsorption/ desorption
In accordance with column 2 of REACH Regulation 1907/2006/EC Annex VIII, the test on adsorption/desorption screening (required in REACh Regulation, Annex VIII, section 9.3.1) does not need to be conducted as the substance can be expected to have a low potential for adsorption based on the octanol water partition coefficient. The theoretical, calculated (EPIWIN) log Pow is -0.46, i.e. very low, as expected for an inorganic salt.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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