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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
other: unspecified data
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
GLP compliance:
no
Medium:
other:
Remarks on result:
other: see 'Remarks'
Remarks:
please refer to "Any other information on results incl. tables"

Solubility of the sample at 25 °C:

 Solvent

 Solubility

 mol/kg

 mol/L

 weight%

 Ethers

 Anisole

 insol.    insol.
 1,2-Diethoxyethane (DEE)  0.01    0.1
 1,2-Dimethoxyethane (DME, Monoglyme)  1.30    25
 Diethyleneglycoldimethylether (Diglyme)  1.30    25
 Diethylether  insol.    insol.
 1,3-Dioxolane  0.02    0.4
 Tetrahydrofuran (THF)  1.90  2.14  37
 2-Methyl tetrahydrofuran (1 -Me-THF)  0.39    8
 Tetrahydropyran (THP)  0.58    11

 Carboantes

 Diethyl carbonate (DEC)

 < 0.01

 

 < 0.1

 Ethyl methyl carbonate (EMC)

 < 0.01

 

 < 0.1

 Dimethyl carbonate (DMC)

 < 0.01

 

 < 0.1

 Ethylene carbonate (EC)

 (1.03)1)

 

 (20)1)

 Propylene carboante (PC)

 1.00

 1.22

 19

 EC/PC/DMC = 1:1:3

 0.67

 0.80

 13

 Carboxylic esters

 Butyl acetate

 0.37

 

 7

 Butyl formiate

 0.11

 

 2

 Ethyl acetate (EA)

 0.98

 

 19

 Methyl acetate (MA)

 0.49

 

 10

 Propyl acetate (PA)

 0.74

 

 14

 Isopropyl acetate (iPA)

 0.79

 

 15

 Other Carbonyles

 Acetone

 1.86

 

 36

 y-Butyrolactone (GBL)

 1.55

 

 30

 N-Methyl-2-pyrrolidone (NMP

1.80

 

 35

 Miscellaneous

 Acetonitrile (AN)

1.10

 1.0

 22

 2-Ethoxyethyl acetate

 0.52

 

 10

 2-Methoxyethyl acetate

 0.97

 

 19

 1-Methoxy-2-propyl acetate

0.75

 

 14.5

 Methanol

 (ca. 1.80)2)

 

 (ca. 35)2)

 i-Propanol

 (1.29)2)

 

 (25)2)

 Water

 (ca. 1.80)2)

 

 (ca. 35)2)

1) Crystalisatzion on longer strorage; 2) decomposition

Conclusions:
Whereas in protic solvents hydrolysis occurs, the substance is indefinitely stable in anhydrous aprotic solvents at temperatures below ca. 150°C.
Executive summary:

Solubility of the sample was tested in different organic solvents at 25 °C. Whereas in protic solvents hydrolysis occurs, the substance is indefinitely stable in anhydrous aprotic solvents at temperatures below ca. 150°C.

Description of key information

Solubility of the sample was tested in different organic solvents at 25 °C. Whereas in protic solvents hydrolysis occurs, the substance is indefinitely stable in anhydrous aprotic solvents at temperatures below ca. 150°C.

Key value for chemical safety assessment

Additional information