Registration Dossier
Registration Dossier
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EC number: 418-240-3 | CAS number: 74401-04-0 N-METHYL-4-(P-FORMYLSTYRYL)-PYRIDINIUM METHYLSULFATE; SBQ; SBQ-SALZ
Endpoint summary
Administrative data
Description of key information
Skin sensitiser
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The skin sensitisation potential of the test substance was evaluated in vivo in a maximisation test on Guinea pigs according to the EU Method B.6 (92/69/EEC) and in compliance with GLP.
More than 60 % of the animals showed a positive response upon an intradermal induction with the test item at 1 % w/v.
The susbtance is considered as a skin sensitiser
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
In the maximisation test on Guinea pigs, more than 60 % of the animals showed a positive response upon an intradermal induction with the test item at 1 % w/v. Therefore, the test substance shall be classified as sub-category 1A skin sensitiser according to the CLP Regulation EC No. 1272/2008
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