Registration Dossier
Registration Dossier
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EC number: 418-240-3 | CAS number: 74401-04-0 N-METHYL-4-(P-FORMYLSTYRYL)-PYRIDINIUM METHYLSULFATE; SBQ; SBQ-SALZ
Endpoint summary
Administrative data
Description of key information
LD50 (oral) > 2000 mg/kg bw
LD50 (dermal) > 2000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Additional information
The acute oral toxicity of the test substance was evaluated in rats in a limit test according to the EU method B.1 (92/69/EEC) and in compliance with GLP. Five animals per sex were dosed at 2000 mg/Kg bw. No mortality occured and no clinical signs as well as no treatment-related macroscopic findings were observed. All animals showed expected gains in bodyweight over the study period.
LD50 (oral) > 2000 mg/kg bw
The acute dermal toxicity of the test substance was evaluated in rats in a semiocclusive limit test according to the EU method B.3 (92/69/EEC) and in compliance with GLP. Five animals per sex were dosed at 2000 mg/Kg bw. No mortality occured and no clinical signs as well as no treatment-related macroscopic findings were observed.
LD50 (dermal) > 2000 mg/kg bw
Justification for classification or non-classification
In the acute oral toxicity test and in the acute dermal toxicity test LD50 was found to be > 2000 mg/kg bw. Therefore, the substance shall not be classified as harmful or toxic according to the CLP Regulation (EC) No. 1272/2008.
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