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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
The preliminary test according to OECD 105 did not work because of the formation of a more or less stable emulsion. A modified version of OECD 105 has therefore been implemented
Principles of method if other than guideline:
The preliminary test according to OECD 105 did not work because of the formation of a more or less stable emulsion. A modified version of OECD 105 has therefore been implemented
GLP compliance:
not specified
Remarks:
not specified in the report
Type of method:
flask method
Key result
Water solubility:
16 mg/L
Conc. based on:
not specified
Incubation duration:
3 wk
Temp.:
20 °C
Remarks on result:
not measured/tested
Remarks:
pH is not given in the study report
Conclusions:
The preliminary test according to OECD 105 did not work because of the formation of a more or less stable emulsion. A modified version of OECD 105 has therefore been implemented. Under the experimental conditions, the water solubility of the sample " DIETHYL SEBACATE Lot 1727003" is 16 mg/L at 20°C
Executive summary:

For that endpoint, one reliable study performed on the registered substance and according to the modified OECD 105 guideline was available.

The preliminary test according to OECD 105 did not work because of the formation of a more or less stable emulsion. A modified version of OECD 105 has therefore been implemented.

After sample preparation, it was injected into a GCMS. The calibration was done with an external standard. The recovery rate was verified by double determination: 105% (104% and 106%).

Under the experimental conditions, the water solubility of the sample " DIETHYL SEBACATE Lot 1727003" is 16 mg/L at 20°C.

The validity criteria were successful and the study was therefore regarded as acceptable for that endpoint.

Description of key information

For that endpoint, one reliable study performed on the registered substance and according to the modified OECD 105 guideline was available.

The preliminary test according to OECD 105 did not work because of the formation of a more or less stable emulsion. A modified version of OECD 105 has therefore been implemented.

After sample preparation, it was injected into a GCMS. The calibration was done with an external standard. The recovery rate was verified by double determination: 105% (104% and 106%).

Under the experimental conditions, the water solubility of the sample " DIETHYL SEBACATE Lot 1727003" is 16 mg/L at 20°C.

The validity criteria were successful and the study was therefore regarded as acceptable for that endpoint.

Key value for chemical safety assessment

Water solubility:
16 mg/L
at the temperature of:
20 °C

Additional information