Registration Dossier
Registration Dossier
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EC number: 258-007-1 | CAS number: 52558-73-3
Endpoint summary
Administrative data
Description of key information
Oral: Data waiving
Inhalation: Data waiving
Dermal: Data waiving
As the registered substance is classified for its skin corrosion properties as Skin Corr. 1B (H314), no acute toxicity studies have to be conducted according to Regulation (EC) No. 1907/2006 (REACH), Annexes VII and VIII, Item 8.5, Column 2.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Regulation (EC) No. 1907/2006 (REACH) stipulates in its Annexes VII and VIII that acute toxicity tests in either route (oral, inhalation or dermal) do not need to be conducted if the registered substance is classified as skin corrosion. Since N-(1-oxotetradecyl)sarcosine (CAS 52558-73-3) is classified as Skin Corr. 1 as a result of reliable in vitro and in vivo data obtained with adequate analouge substances, testing for acute toxicity is deemed not suitable and necessary. As a result of the skin corrosion properties, contact by any route of exposure to the substance must be avoided and effects of acute toxicity - if any - are avoided as well.
Justification for classification or non-classification
In the absence of appropriate measured data, N-(1-oxotetradecyl)sarcosine (CAS 52558-73-3) is not classified for acute toxicity due to lack of information.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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