Registration Dossier
Registration Dossier
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EC number: 284-965-5 | CAS number: 85005-32-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 29 July to 13 August 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Read-across from an analogue substance for which a guideline study (Klimish =1) is available.
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
See attached reporting format. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOELR
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks:
- and yield
- Remarks on result:
- other: Based on the read-across from an analogue substance
- Conclusions:
- Based on the read-across from an analogue substance, the 72h- No Effect Loading Rate of the target substance in green algae was determined to be 100 mg/l loading rate WAF.
- Executive summary:
A study was performed to assess the effect of an analogue substance on the growth of the green alga Desmodesmus subspicatus. The method followed that described in the OECD guideline 201 and was conducted in accordance to GLP standards. The No Observed Effect Loading Rate of the test subtance was 100 mg/l loading rate WAF (Water Accommodated Fractions) based on growth rate and yield. Based on the read-across approach, the 72h-NOELR of the target subtance was determined to be 100 mg/L loading rate WAF.
Reference
Description of key information
Key study: Test method according to OECD 201. GLP study. Based on the read-across approach the 72h-NOELR of the substance was determined to be 100 mg/L loading rate WAF.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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