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EC number: 629-765-4
CAS number: 1226892-44-9
Based on the limited number of acute fish data it can be observed that fish are not more sensitive than daphnia and algae to amidoamines/imidazolines. For the calculation of the PNECaquatic bulk it is considered unlikely that fish toxicity will be critical for amidoamines/imidazolines category. Hence any additional toxicity testing with fish will not add scientific value to the ecotoxicity profile of this category other than for obtaining a lower assessment factor. It is therefore concluded that for scientific reasons and in accordance to REACH legislation further testing on fish has to be avoided for reasons of animal welfare and that based on the weight of evidence available on ecotoxicity data for several cationic surfactants a safety factor of 10 may be applied for the derivation of the PNECaquatic,bulk.
limited number of short-term toxicity fish tests available were
conducted in a period when no reliable specific method of analyses was
available. The concentrations were therefore in old studies not
analytically verified. The reliability of these results is limited
because of the poor solubility of the test substances and partial
sorption onto the walls of test vessels. In one study however the
exposure concentration was quantified and this study has been selected a
Key study. The other two were considered to be valid with restrictions
and can be used as supporing studies.
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