Registration Dossier
Registration Dossier
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EC number: 402-920-1 | CAS number: 103300-89-6 N-6-TRIFLUORACETYL-L-LYSYL-L-PROLIN; T.F.A. LYS PRO; TFA-LYS-PRO
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993-05-17 to 1993-05-18
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 1984
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 hPa
- Remarks on result:
- other: extrapolated from the measured data using the Antoine constants A, B and C
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 hPa
- Remarks on result:
- other: extrapolated from the measured data using the Antoine constants A, B and C
- Key result
- Temp.:
- 50 °C
- Vapour pressure:
- 0 hPa
- Remarks on result:
- other: extrapolated from the measured data using the Antoine constants A, B and C
- Conclusions:
- In a GLP study conducted according to Directive 84/449/EEC of 24 April 1984, Method A.4 (vapour pressure balance), the vapour pressure was determined to be 2.0 E-5 hPa at 25 °C.
Reference
Above 70 °C melting of the test substance was observed due to the typical temperature course of the melting process. Vapour pressures between 70 and 88 °C are lower then the value measured at 68 °C and show a slight temperature dependence. For the extrapolation to the lower temperatures as shown in the table, the data measured above 70 °C were not considered. The measured vapour pressure data were evaluated in the temperature range between 52,9 and 68,2 °C.
Description of key information
Key value for chemical safety assessment
Additional information
In a GLP study conducted according to Directive 84/449/EEC of 24 April 1984, Method A.4 (vapour pressure balance), the vapour pressure was determined to be 2.0 E-5 hPa at 25 °C.
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