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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

A key study evaluating the toxicity of Amber Core (P-#620) to activated sludge is available. The 3h-EC50 was determined to be greater than 100 mg/L, the highest tested level.

Key value for chemical safety assessment

EC50 or LC50 for microorganisms:
100 mg/L

Additional information

One key study according to the OECD Guideline 209 and EC Directive 87/302 with GLP standards is available on the respiration rate of activated sludge. Samples of activated sludge, fed with synthetic sewage, were exposed to Amber Core (P-#620) for 3 hours. Their rates of oxygen consumption were determined and compared with those of controls, containing activated sludge and synthetic sewage alone. Two tests were conducted: a preliminary screen and a final limit test in which triplicate vessels at 100 mg/L. The results based on the specific respiration rates of the control cultures and the positive control 3,5-DCP show that the tests were valid and that the samples of activated sludge employed were sensitive to inhibition. Amber Core had no significant inhibitory effect on the respiration rate of activated sludge at any of the concentrations employed in the test. The highest level of inhibition (10%) occurred in one replicate at 100 mg/L in the final test. The EC50 of the test material could not therefore be calculated but these must be greater than 100 mg/L, the highest tested level.