Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 412-300-2 | CAS number: 139504-68-0 AMBER CORE
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
A key study evaluating the toxicity of Amber Core (P-#620) to activated sludge is available. The 3h-EC50 was determined to be greater than 100 mg/L, the highest tested level.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
Additional information
One key study according to the OECD Guideline 209 and EC Directive 87/302 with GLP standards is available on the respiration rate of activated sludge. Samples of activated sludge, fed with synthetic sewage, were exposed to Amber Core (P-#620) for 3 hours. Their rates of oxygen consumption were determined and compared with those of controls, containing activated sludge and synthetic sewage alone. Two tests were conducted: a preliminary screen and a final limit test in which triplicate vessels at 100 mg/L. The results based on the specific respiration rates of the control cultures and the positive control 3,5-DCP show that the tests were valid and that the samples of activated sludge employed were sensitive to inhibition. Amber Core had no significant inhibitory effect on the respiration rate of activated sludge at any of the concentrations employed in the test. The highest level of inhibition (10%) occurred in one replicate at 100 mg/L in the final test. The EC50 of the test material could not therefore be calculated but these must be greater than 100 mg/L, the highest tested level.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
