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Environmental fate & pathways

Hydrolysis

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Description of key information

Based on the results obtained in the pre-test (5d at 50 °C), Olaflur can be characterised as stable at pH 4, 7 and 9.

Key value for chemical safety assessment

Additional information

Abiotic degradation (hydrolysis) of Olaflur was investigated according to OECD guidelines for the Testing of Chemicals, No. 111 (Hydrolysis as a function of pH). The test conditions applied were based on the conditions specified in the OECD guideline for the preliminary test (Tier 1): pH: 4.0 / 7.0 / 9.0, Temperature: 50 °C, Duration: 5 days. Hydrolysis of Olaflur was characterised based on quantification of the fatty acid amines by HPLC-ESI-MS. Evaluation of hydrolysis at pH 7: Olaflur can be characterised as stable under the applied test conditions. No significant hydrolysis for the five quantified alkyl amines is assumed to occur at neutral pH 7. Evaluation of hydrolysis at pH 9: Low contents were especially observed for the alkyl amines with the side chains miristyl and linolyl. However, even for these two species, the observed reduction of the content with respect to t = 0 (not incubated control solutions with Olaflur) is only slightly greater than 10 %. A varying, but only minor degree of hydrolysis for the five quantified alkyl amines may occur at basic pH 9. Evaluation of hydrolysis at pH 4: Re-Test at pH 4: Problems/variation noted in a first test were due to the buffer system and potentially glass vessels used. The test substance Olaflur can be characterised as stable under the applied test conditions (HCl instead of phthalate buffer system, PVC containers). No significant hydrolysis for the five quantified alkyl amines is assumed to occur at pH 4.