Registration Dossier
Registration Dossier
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EC number: 700-792-4 | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 May 2012 - 03 September 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Experimental study conducted in GLP compliant lab according to EC and OECD test methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
Test material
- Reference substance name:
- Reaction mass of 1,2,2,6,6-pentamethylpiperidin-4-yl hexadecanoate and 1,2,2,6,6-pentamethylpiperidin-4-yl octadecanoate
- EC Number:
- 700-792-4
- Molecular formula:
- C26H51NO2, C28H55NO2
- IUPAC Name:
- Reaction mass of 1,2,2,6,6-pentamethylpiperidin-4-yl hexadecanoate and 1,2,2,6,6-pentamethylpiperidin-4-yl octadecanoate
- Test material form:
- other: white to pale yellow solid
- Details on test material:
- - Name of test material (as cited in study report): T-1640L
- Physical state: white to pale yellow solid
- Analytical purity: 98.74%
- Purity test date:
- Lot/batch No.: 10121
- Expiration date of the lot/batch: 12 April 2013
- Stability under test conditions: stable
- Storage condition of test material: refrigerated in the dark under dry conditions
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- < 0.05 mg/L
- Temp.:
- 20 °C
- pH:
- >= 6.4 - <= 7
- Details on results:
- The detector calibration was found to be linear over the range 0 to 5 mg/l of standard
solutions in chloroform with a regression coefficient of 0.9981.
A summary of the results of the test and shows that the water solubility of
T-1640L is less than 0.05 mg/l. The primary data for this test is also presented.
A mean recovery of approximately 117% of T-1640L from fortified control samples was
achieved and deemed to be acceptable at the low solubility level, whilst no significant
interfering peaks were evident in blank control solutions.
Applicant's summary and conclusion
- Conclusions:
- T-1640L was found to have a water solubility of less than 0.05 mg/l at 20°C.
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