Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Remarks:
peer-reviewed monograph

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2006

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
not specified, methods can be inferred from the results
GLP compliance:
not specified
Test type:
other: Test type not provided
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Ammonium glycyrrhizate
EC Number:
258-887-7
EC Name:
Ammonium glycyrrhizate
Cas Number:
53956-04-0
Molecular formula:
C42H65NO16
IUPAC Name:
ammonium glycyrrhizate

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
not specified
No. of animals per sex per dose:
not specified
Control animals:
not specified
Details on study design:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
12 700 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The test item has a very low acute toxicity (oral) with an LD50 of 12700 mg/kg in mice.