Registration Dossier
Registration Dossier
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EC number: 614-406-6 | CAS number: 68308-61-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-h EC50 based on growth rate was determined as 105.64 mg/L. The overall NOEC was determined to be 12.5 mg/L.
Key value for chemical safety assessment
Additional information
The purpose of this study was to determine the effect of the test item GARDO TP 10451 on the growth of an unicellular green algal species Pseudokirchneriella subcapitata (formerly: Selenastrum capricornutum). Exponentially growing cultures of Pseudokirchneriella subcapitata were exposed to various concentrations of the test item over several generations under defined conditions. The algal growth in relation to a control culture was determined over a fixed test period of 72 hours and thus, over several algal generations. The test method of application and the test species Pseudokirchneriella subcapitata are recommended by the test guidelines. The nominal test item concentrations were: 6.25; 12.5; 25; 50 and 100 mg/L. Agreed with the Sponsor analytical measurements of the test item concentrations were not performed during this study because the calculative highest solubility of GARDO TP 10451 (1.1734 ng/L) is below the lowest level of quantification. Therefore, all reported biological results are related to the nominal concentrations. The 72-h EC50 based on growth rate was determined as 105.64 mg/L. The overall NOEC was determined to be 12.5 mg/L.
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