Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Carcinogenicity
Administrative data
Description of key information
Substance specific data on carcinogenicity is not required for substances registered as transported isolated intermediate >1000 t/a according to Annex VII of REACH regulation. Since the registered substance Alkaline co-precipitation products of soluble cobalt, manganese and nickel salts and the different constituents of the UVCB release the same toxicological relevant unit under physiological relevant conditions, the overall toxicity of dissolved nickel, cobalt and manganese ions can be used to assess the toxicity of the registered substance for endpoints where substance specific data is not required. Therefore, data from Nickel dihydroxide, Cobalt dihydroxide, Tricobalt tetraoxide, Trimanganese tetraoxide and Manganese dioxide are used for hazard assessment based on a worst-case mixture approach.
Nickel dihydroxide is classified for carcinogenicity via inhalation as Carc. 1A (H350i) under the 1st ATP to the CLP and Cobalt dihydroxide is classified as Carc. 1B (H350i) under Regulation (EC) No. 1272/2008. No data on carcinogenicity is available for Tricobalt tetraoxide, Trimanganese tetraoxide and Manganese dioxide is available.
Key value for chemical safety assessment
Justification for classification or non-classification
Based on the mixture approach, the registered substance is classified for carcinogenicity via inhalation as Carc. 1A (H350i) under Regulation (EC) No. 1272/2008.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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