Registration Dossier
Registration Dossier
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EC number: 203-526-0 | CAS number: 107-85-7
Endpoint summary
Administrative data
Description of key information
Additional information
Saturated primary aliphatic amines are generally stable towards hydrolysis, oxidation and photolysis. In amines the bond between the terminal (saturated) carbon atom and the nitrogen atom (single bond) is polarized with a positive partial charge at the carbon atom. The positively charged carbon atom is in principle capable to undergo nucleophilic substitution with an electron rich species (for example strong bases). Water exhibits nucleophilic properties, but it is not a strong enough nucleophile to generate an efficient reaction with amines under ambient conditions. The energy barrier for the nucleophilic substitution reaction is too high to be overcome (GUBDH, 2008; OXEA, 2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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