Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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Reaction mass of (1R,4S,4aR,8R,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8S,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1R,4S,4aR,8S,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one and (1S,4R,4aS,8R,8aR)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one
EC number: 700-770-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
Available information:
Local lymph node assay (LLNA, screening level study) in the mouse: negativeOnly a screening level study is available for skin sensitisation. The result given above provides useful information about the corresponding properties of the substance. However the reliability, relevance and adequacy of the data are considered as limited and an overall reliability rating of 3 (= not reliable, according to the scoring system of Klimisch et al.) has been assigned. As a consequence, these data are not adequate for risk assessment and classification and labelling purposes.
Migrated from Short description of key information:
Local lymph node assay (LLNA, screening level study): negative
Respiratory sensitisation
Endpoint conclusion
- Additional information:
No data available.
Migrated from Short description of key information:
No data available.
Justification for classification or non-classification
Skin sensitisation: Due to the low overall reliability rating of the available study (see above under "Discussion"), the corresponding data are not adequate for a definitive decision about classification. Based on the available information the substance does not meet the criteria for classification as "skin sensitiser" under Regulation (EC) 1272/2008, Annex I, Part 3, 3.4.2.2; reason for non-classification: inconclusive.
Respiratory sensitisation: no data available. Based on the available information the substance does not meet the criteria for classification as "respiratory sensitiser" under Regulation (EC) 1272/2008, Annex I, Part 3, 3.4.2.1; reason for non-classification: data lacking.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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