Registration Dossier
Registration Dossier
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EC number: 473-370-8 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 October 2007 to 23 January 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Radiolabelling:
- no
- Test temperature:
- 35 ˚C
- Details on study design: HPLC method:
- Instrument Alliance Separation Module 2695 (Waters, Milford, MA, USA)
Detector Dual lambda Absorbance Detector 2487(Waters)
Column 125 mm X 4.6 mm i.d., Hypersil BDS-CN; dp: 5 um (Thermo, San Jose CA USA)
Column temperature 35 ˚C
Injection volume 10 µL
Mobile phase 55/45 (v/v) methanol/water
Flow 1.0 mL/min
UV detection 210 nm - Analytical monitoring:
- no
- Type:
- log Koc
- Value:
- < 1.32 dimensionless
- pH:
- 7
- Temp.:
- 35 °C
- Remarks on result:
- other: HPLC method
- Type:
- Koc
- Value:
- < 20.9 dimensionless
- pH:
- 7
- Temp.:
- 35 °C
- Details on results (HPLC method):
- Retention times of reference substances used for calibration: see attached table
One peak was found with a retention time of 2.287 min
- Transformation products:
- not measured
- Conclusions:
- The logKoc of the substance is < 1.32
- Executive summary:
In the HPLC method the logKoc of the substance was determined to be < 1.32
Reference
Description of key information
In the HPLC method the logKoc of the substance was determined to be < 1.32
Key value for chemical safety assessment
- Koc at 20 °C:
- 20.9
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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