Citric acid, sodium titanium salt

Auto flammability

Link to relevant study record(s)

Reference

Endpoint:

auto-ignition temperature (liquids)

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Justification for type of information:

HYPOTHESIS FOR THE ANALOGUE APPROACH
There is a mechanistic reasoning to the read-across. The target substance, citric acid, sodium titanium salt (Tyzor Activate 422) hydrolyses rapidly upon contact with water or moisture. The complete hydrolysis will take place with no significant reaction products other than sodium citrate and hydrated titanium dioxide.
Therefore, read-across from the existing physicochemical studies (partition coefficient) on the source substance is considered as an appropriate adaptation to the standard information requirements of Annex VII of the REACH regulation.

ANALOGUE APPROACH JUSTIFICATION
Physicochemical data shows that the physicochemical profiles of the target and source substance are similar as outlined in the data matrix.
The target substance (Tyzor Activate 422) is hydrolytically unstable. Due to a rapid hydrolysis octanol-water partition coefficient is not technically feasible to test for the target substances. . Thus, partition coefficient n-octanol/water (Log Kow) of citric acid is used to improve the understanding on physico-chemical properties of the target substance. Due to a rapid hydrolysis citric acid data is used to fulfil endpoint requirements of self-ignition temperature.

DATA MATRIX
See IUCLID section 13.2. for data matrix

Reason / purpose for cross-reference:

read-across source

Principles of method if other than guideline:

Information on the method not available.

GLP compliance:

not specified

Key result

Auto-ignition temperature:

1 010 °C

Atm. press.:

760 mm Hg

Conclusions:

A self-ignition temperature of 1010°C is reported for citric acid in SIDS dataset. The original reference was not available for review and no further information is available.

Description of key information

No study available of the target substance.

Self ignition temperature of citric acid (hydrolysis product of the target substance) is 1010 deg. C. at normal atmospheric pressure i.e. 760 mm Hg.

The target substance, citric acid, sodium titanium salt (Tyzor AC420) hydrolyses rapidly upon contact with water or moisture. The complete hydrolysis will take place with no significant reaction products other than sodium citrate and hydrated titanium dioxide.