Hop, Humulus lupulus, ext.

Explosiveness

Link to relevant study record(s)

Reference

Endpoint:

explosiveness, other

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2 to 4 October 2017

Reliability:

1 (reliable without restriction)

Qualifier:

according to guideline

Guideline:

other:

Version / remarks:

The testing laboratory is GLP compliant and the test was carried out according to the principles of GLP. An internal standard operating procedure was followed for the direct scanning calorimetry tests.

Principles of method if other than guideline:

Date 02/10/2017
SOP Reference CTL SOP 320
Test System DSC System 1
Test Filename DSC4028001957A
Crucible Type Gold-lined steel (high pressure, sealed)
Sample Preparation Tested as received
Start Temperature -40°C
Trip Temperature 400°C
Ramp Rate 4 K.min-1
Test Atmosphere Air
Sample Mass 4.7 mg

GLP compliance:

yes

Specific details on test material used for the study:

Hop extract batch number 160025. This is a liquid carbon dioxide extract of hops variety 'Cascade'.

Key result

Parameter:

other: The material does not fulfil the criteria for explosiveness. The exothermic events observed in the DSC trace have heats of decomposition of less than 300 J per g.

Remarks on result:

other: The material does not fulfil the criteria for explosiveness. The exothermic events observed in the DSC trace have heats of decomposition of less than 300 J per g.

Notes from the test report: "The sample was observed to undergo an exothermic event from 60.3°C which had a heat of decomposition of -24.7 J.g-1. A second exothermic event was then observed to commence from 138.0°C which had a heat of decomposition of -157.7 J.g-1. No further significant energetic events were noted up to 400°C."

The DSC plot is attached - see "Illustration (picture/graph)"

Interpretation of results:

GHS criteria not met

Conclusions:

The DSC trace for hop extract shows two exothermic events: one at 60.3 oC with a heat of decomposition of -24.7 J per g, and one at 138.0 oC with a heat of decomposition of -157.7 J per g. No further significant energetic events were noted up to 400 oC. The exothermic decomposition is less than 500 J per g (Regulation (EC) 1272/2008, Annex I, Part 2, 2.1.4.3 (c)), so the material is not explosive, and it is less than 300 J per g (Regulation (EC) 1272/2008, Annex I, Part 2, 2.8.2.1) so it is not self-reactive.

Key value for chemical safety assessment

Explosiveness:

non explosive