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EC number: 210-123-3 | CAS number: 606-68-8
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19 October 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Version / remarks:
- 2012
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Version / remarks:
- Regulation EC No. 440/2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Version / remarks:
- 2002
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- air comparison pycnometer (for solids)
Test material
- Reference substance name:
- Dihydronicotinamide-adenine dinucleotide, disodium salt
- EC Number:
- 210-123-3
- EC Name:
- Dihydronicotinamide-adenine dinucleotide, disodium salt
- Cas Number:
- 606-68-8
- Molecular formula:
- C21H27N7O14P2.2Na
- IUPAC Name:
- disodium [(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl ({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
- Reference substance name:
- Dihydronicotinamide-adenine dinucleotide
- EC Number:
- 200-393-0
- EC Name:
- Dihydronicotinamide-adenine dinucleotide
- Cas Number:
- 58-68-4
- Molecular formula:
- C21H29N7O14P2
- IUPAC Name:
- [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Oxidane
- Test material form:
- solid: crystalline
- Remarks:
- crystaline powder
- Details on test material:
- Batch No.: 18243100
Storage conditions: Store at -15 to -25°C,
Handling: Keep frozen on dry ice.
Constituent 1
impurity 1
impurity 2
Results and discussion
Density
- Key result
- Type:
- relative density
- Density:
- 1.955 other: dimensionless
- Temp.:
- 20 °C
- Remarks on result:
- other: the density of the test item is given as the mean value of four measurements.
Any other information on results incl. tables
The individual relative density measurements were 2.02182 g/cm3 (test 1), 1.90324 g/cm3 (test 2), 1.98202 g/cm3 (test 3) and 1.91366 g/cm3 (test 4).
Applicant's summary and conclusion
- Conclusions:
- According to OECD Test Guidelines 109 (2012) and EC No. 440/2008 Part A. Method A.3., and OCSPP Test Guideline 830.7300 (2002), the relative density of the test item beta-NADH, disodium salt (CAS no. 606-68-8) at 20 °C ± 0.01 °C (compared to water at 4 °C) was determined to be 1.955.
- Executive summary:
According to OECD Test Guidelines 109 (2012) and EC No. 440/2008 Part A. Method A.3., and OCSPP Test Guideline 830.7300 (2002), the relative density of the test item beta-NADH, disodium salt (CAS no. 606-68-8) at 20 °C ± 0.01 °C (compared to water at 4 °C) was determined to be 1.955.
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