Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-123-3 | CAS number: 606-68-8
Surface tension
Administrative data
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Version / remarks:
- Regulation EC No. 440/2008
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- ring method
Test material
- Reference substance name:
- Dihydronicotinamide-adenine dinucleotide, disodium salt
- EC Number:
- 210-123-3
- EC Name:
- Dihydronicotinamide-adenine dinucleotide, disodium salt
- Cas Number:
- 606-68-8
- Molecular formula:
- C21H27N7O14P2.2Na
- IUPAC Name:
- disodium [(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl ({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
- Reference substance name:
- Dihydronicotinamide-adenine dinucleotide
- EC Number:
- 200-393-0
- EC Name:
- Dihydronicotinamide-adenine dinucleotide
- Cas Number:
- 58-68-4
- Molecular formula:
- C21H29N7O14P2
- IUPAC Name:
- [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Oxidane
- Test material form:
- solid: crystalline
- Remarks:
- crystaline powder
- Details on test material:
- Batch No.: 18243100
Storage conditions: Store at -15 to -25°C,
Handling: Keep frozen on dry ice.
Constituent 1
impurity 1
impurity 2
Results and discussion
Surface tension
- Key result
- Surface tension:
- 69.22 mN/m
- Temp.:
- 20 °C
- Conc.:
- 1.022 g/L
- Remarks on result:
- other: overall mean of first measurement (6 values measured) and second measurement (6 values measured) concentration refers to nominal concentration of the test item
Any other information on results incl. tables
The detailed results of two measurements are summarized in the table below.
| Value No. | First measurement; 15 min after preparation of the solution (mN/m) | Second measurement; 5 min after preparation of the solution (mN/m) |
| 1 | 69.48 | 69.04 |
| 2 | 69.47 | 69.01 |
| 3 | 69.44 | 69.02 |
| 4 | 69.43 | 69.00 |
| 5 | 69.41 | 69.01 |
| 6 | 69.38 | 68.99 |
| Mean value of the individual values | 69.44 +- 0.04 | 69.01 +- 0.02 |
| Total mean value | 69.22 +- 0.30 | |
Applicant's summary and conclusion
- Conclusions:
- According to OECD Test Guideline 115 and Regulation EC No. 440/2008 Part A Method A.5. the surface tension at 20°C of the test item beta-NADH, disodium salt (CAS 606-68-8) was determined to be 69.22 mN/m. According to Regulation EC No. 440/2008 Part A Method A.5. the test item is not to be regarded as surface active material.
- Executive summary:
According to OECD Test Guideline 115 and Regulation EC No. 440/2008 Part A Method A.5. the surface tension at 20°C of the test item beta-NADH, disodium salt (CAS 606-68-8) was determined to be 69.22 mN/m. According to Regulation EC No. 440/2008 Part A Method A.5. the test item is not to be regarded as surface active material.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
