Registration Dossier
Registration Dossier
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EC number: 238-262-5 | CAS number: 14320-04-8
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient details provided.
Data source
Reference
- Reference Type:
- publication
- Title:
- Formulation of a zinc(II)-phthalocyanine-containing topical gel for photodynamic therapy of hyperproliferative skin conditions
- Author:
- Lowe WG
- Year:
- 1 997
- Bibliographic source:
- Drug Dev. Ind. Pharm.; VOL 23 ISS 7 1997, P705-710
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Executive summary:
Only a limited number of solvents were able to solubilize the dye to any extent and of these, the most suitable for formulation purposes was N-methylpyrrolidone (N-methyl-2-pyrrolidone). Under standard storage conditions, there was little or no degradation or aggregation of the dye in this formulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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