Registration Dossier
Registration Dossier
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EC number: 282-208-3 | CAS number: 84144-87-6 Flue dust and ash containing vanadium resulting from the combustion of vanadium-bearing fuel oil.
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity was assessed in an acute toxic class method according to OECD 423 (BSL 2010a)
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 500 mg/kg bw
Additional information
In an acute oral toxicity study, groups (3or 6/sex) of female Wistar rats were given a single oral dose of Ashes (residues), vanadium-contg. in water at doses of 2000 or 300 mg/kg bw. Animals were then observed for 14 days. The test material is classified as harmful based on an Oral LD50 cut-off = 500 mg/kg bw.
This acute oral study is classified as acceptable. It does satisfy the guideline requirement for an acute oral toxicity study OECD 423 in the rats
Justification for classification or non-classification
According to the CLP-Regulation (EC) No 1272/2008 the test substance is classified Acute Tox. 4 based on an LD50 of 500 mg/kg.
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