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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1973
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Limited documentation of the study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973
Report date:
1973

Materials and methods

Test guideline
Guideline:
other: OSHA Toxicity Screening Test
GLP compliance:
no
Remarks:
pre-GLP
Test type:
other: single dose
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Isodecyl methacrylate
EC Number:
249-978-2
EC Name:
Isodecyl methacrylate
Cas Number:
29964-84-9
Molecular formula:
C14H26O2
IUPAC Name:
8-methylnonyl methacrylate

Test animals

Species:
rabbit
Strain:
New Zealand White

Administration / exposure

Doses:
3000 mg/kg
No. of animals per sex per dose:
6

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
> 3 000 mg/kg bw
Based on:
test mat.
Mortality:
In the observation period of 14 days, 2 of 6 experimental animals died.
Clinical signs:
other: As signs of intoxiciation, only hypoactivity was reported.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met