Registration Dossier
Registration Dossier
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EC number: 205-471-8 | CAS number: 141-23-1
Endpoint summary
Administrative data
Description of key information
The substance is not expected to exhibit toxicity in the aquatic environment. The substance has a very low water solubility (i.e., 0.08994 mg/L) and is considered insoluble in water. Short-term toxicity was not observed in any of the aquatic toxicity tests conducted on an analogue substance through read-across at three trophic levels; in addition, long-term toxicity was not observed in algae. The substance has been determined to be readily biodegradable (i.e., 80% degradation in 28 d and meeting the 10-d window) and is not persistent in the environment; therefore, food chain exposures through secondary poisoning are not expected. Furthermore, studies conducted on analogue substances in higher vertebrates showed that the substance is not expected to exhibit acute oral toxicity, specific target organ toxicity through single or repeated dose oral exposure, genetic toxicity or reproductive toxicity. The substance is a short-chain alkyl ester of a naturally occurring fatty acid (i.e., the methyl ester of 12-hydroxystearic acid), and is expected to undergo catabolism by esterases and lipases in vivo; toxicokinetic studies conducted on analogue substances in mammals demonstrated a pharmacokinetic disposition comparable to that of endogenous triglycerides.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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