Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1993

Materials and methods

Results and discussion

Any other information on results incl. tables

Ingestion of cupric sulfate in drinking water or feed produced hyperplasia and hyperkeratosis of the forestomach mucosa in both rats and mice. The no-effect level (NOEL) for this lesion was 1000 ppm in rats and 2000 ppm in mice.

Applicant's summary and conclusion

Conclusions:
Ingestion of cupric sulfate in drinking water or feed produced hyperplasia and hyperkeratosis of the forestomach mucosa in both rats and mice. The no-effect level (NOEL) for this lesion was 1000 ppm in rats and 2000 ppm in mice.