Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
publication
Title:
Range-Finding Toxicity Data: List VIII
Author:
Toxikology and applied Pharmacology ( Charles P.Carpenter)
Year:
1974

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methylcrotonic acid
EC Number:
208-782-7
EC Name:
3-methylcrotonic acid
Cas Number:
541-47-9
Molecular formula:
C5H8O2
IUPAC Name:
3-methylbut-2-enoic acid

Test animals

Species:
rabbit

Results and discussion

Applicant's summary and conclusion

Conclusions:
The single skin penetration LD50 of the test item is 3.2 ml/kg.