Registration Dossier
Registration Dossier
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EC number: 204-683-8 | CAS number: 124-13-0
Endpoint summary
Administrative data
Description of key information
In accordance with REACH Annex XI, Section 3, there is no need to further investigate the effects of octanal in terrestrial toxicity studies because the exposure to octanal is absent or not significant (RCR < 1).
Additional information
In accordance with REACH Regulation (EC) No 1907/2006, Annex XI, Section 3, exposure of terrestrial organisms to octanal is not significantand the testing for terrestrial toxicity is therefore omitted. The registered substance is readily biodegradable (75% biodegradation after 28 days), therefore octanal does not persist in the environment. Sorption to sediment, soil, and other organic matter is moderate, based on a predicted log Koc of 2.63 (QSAR), thus the sediment/soil compartment is not expected to be a major route of exposure for this substance. The vapour pressure of the octanal is 148.29 Pa at 25 °C, thus air is a relevant compartment for the distribution of the compound. In fact, octanalis a fragrance substance incorporated into a variety of fragranced products. It is used in industrial, professional and consumer settings.Furthermore, octanal has a low potential for bioaccumulation based on a log Kow ≤4.5 (log Kow = 3.5) and an estimated BCF of 94.69 L/kg wet-wt (QSAR). The acute aquatic toxicity tests, available for three trophic levels, determined no effect concentrations < 1 mg/ (lowest acute effect in aquatic invertebrates, LC50 (48 h) = 1.54 mg/L). The substance is only partially miscible in water and readily biodegradable, thus greater aquatic toxicity in long-term tests is unlikely.
In conculsion: There is no indication for high adsorption or high persistence of the substance in soil. Furthermore, there is no indication from the available acute aquatic toxicity data that the substance is very toxic to aquatic organisms. Therefore a PEC/PNECscreen based on EPM was performed. PNECs were derived for the aquatic compartment by use of the lowest LC50 value observed in the toxicity study on aquatic invertebrates. A PNEC soil was calculated based on the equilibrium partitioning method.The calculated PEC/PNEC ratios for the terrestrial compartment were < 1 for all uses. In conclusion, the environmental exposure assessment for the substance indicates no risk for the terrestrial compartment (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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