1-(2,2,4-trimethyl-1-quinolyl)ethanone

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

13 Jul - 9 Sep 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Hess. Ministerium für Umwelt, Klimaschutz, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

1-(2,2,4-trimethyl-1,2-dihydroquinolin-1-yl)ethan-1-one

EC Number:

665-911-3

Cas Number:

5855-23-2

Molecular formula:

C14 H17 N O

IUPAC Name:

1-(2,2,4-trimethyl-1,2-dihydroquinolin-1-yl)ethan-1-one

Results and discussion

Melting / freezing point

Melting / freezing pt.:

< -50 °C

Decomposition:

no

Remarks on result:

not determinable because of methodological limitations

Remarks:

The test item had no melting point above -50 °C.

Any other information on results incl. tables

Individual results
The test item was cooled down to -80 °C with a cooling rate of 1 K/min, -80 °C were kept for 120 min and 300 min, respectively, and afterwards the test item was heated up to 500 °C and 25 °C, respectively with a heating rate of 10 K/min. During heating up the measurements showed a small endothermal effect (<5 J/g) in the temperature range of (-50) -(-25) °C. No exothermal effect indicating a solidification was observed prior to the endothermal effect. The onset temperature (see Table below) was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline.

The results are summarized in the Table below:

Ident No.	Test item / mg	Starting temp / °C	Final test temp / °C	Temp. range (endothermal) / °C	Onset (melting) /°C	Crucible	Observations after the measurement
39149	16.25	-80	500	(-40) - (-25)	-38.68	Aluminium with a hole	-
39153	21.63	-80	25	(-50) - (-30)	-43.10	Aluminium with a hole	-

Due to the small endothermal effect and the fact, that no exothermal effect for solidification was observed before the endothermal effect an additional quick test was performed to verify the melting point.

 

Melting point / melting range: Quick test
The test item was cooled down to approximately -75 °C. During cooling down the test item solidified. Afterwards the temperature rose steadily. At approximately -40 °C the test item started to soften. From approximately -40 °C to approximately 0 °C the test item continued to soften and became a liquid. No melting point was observed. The steady rise of the temperature without any disturbances also indicated the absence of a melting point. This confirmed the hypothesis that the observed energy in the DSC measurements was too small for a melting point. The test item showed solidification at lower temperatures and became a liquid as the test item warmed up; however no precise temperature range can be given for this process. Due to the results from the DSC-measurements and the quick test it was concluded that the test item had no melting point above -50 °C.