1-(2,2,4-trimethyl-1-quinolyl)ethanone

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

10 Aug - 11 Aug 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Hessisches Ministerium für Umwelt, Klimaschutz, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany

Type of method:

OECD harmonised ring method

Test material

Test material information

Constituent 1

Reference substance name:

1-(2,2,4-trimethyl-1,2-dihydroquinolin-1-yl)ethan-1-one

EC Number:

665-911-3

Cas Number:

5855-23-2

Molecular formula:

C14 H17 N O

IUPAC Name:

1-(2,2,4-trimethyl-1,2-dihydroquinolin-1-yl)ethan-1-one

Results and discussion

Surface tension

Surface tension:

57.2 mN/m

Temp.:

20 °C

Conc.:

92 mg/L

Remarks on result:

other: 90 % of the saturation concentration. The concentrations of the two solutions were determined by HPLC analyses (results: 86 mg/L for Test solution 1 and 98 mg/L for Test solution 2).

Any other information on results incl. tables

Individual Results of the Determination of the Concentration by HPLC
The HPLC data of the two solutions (Test solution 1 and Test solution 2) of the test item (HPLC dilution factor 10) are given in the Table below.

Table HPLC data: determination of the test item concentration

Name	Amount Reference mg/L	Area mAU*min	Dilution Factor	Slope (C1)	Slope Used (C1)	Content mg/L	Mean mg/L
Reference-2 Dil.1	12.252	7.248835278		0.59160568
Reference-2 Dil.1	12.252	7.25669402		0.59228649	0.59194608
Testsolution 1 Dil 1 Resp		5.09064629	10		0.59194608	85.9985
Testsolution 1 Dil 1 Resp		5.07856804	10		0.59194608	85.7944	85.8965
Testsolution 2 Dil 1 Resp		5.78791377	10		0.59194608	97.7777
Testsolution 2 Dil 1 Resp		5.78519753	10		0.59194608	97.7318	97.7548
blank		not detected	10
blank		not detected	10

Results (rounded): 86 mg/L (Test solution 1)

98 mg/L (Test solution 2)

 

Slope = Peak Area (Reference)/ Amount Reference (mg/L)

Content (mg/L) = (Peak Area (Sample) x Dil. factor)/ Slope (Mean Group)

Slope (Mean Group) = Mean value of slope factors (Group)

Individual Results of the Measurement of the Surface Tension
The surface tension values of the two aqueous solutions of the test item were determined.  The measurement was carried out at 20 °C ± 0.5 °C.
A correction factor (Harkins & Jordan) is included. 
The age of the test solutions at the beginning of the measurement was 28.75 hours for the Test solution 1 and 30.0 hours for the Test solution 2. The age of the test solution is defined as the period of time from the preparation of the solution to the recording of the surface tension value. The measured data are given in Table below.

Table: Surface tension of test item, technical substance, measured data

	Experiment 1		Experiment 2
	Time [s]	σM [mN/m]	Time [s]	σM [mN/m]
1. measurement	73.5	57.22	71.6	55.99
2. measurement	114.2	57.19	112.8	55.89
3. measurement	156.7	57.18	154.6	55.86
4. measurement	194.1	57.20	194.4	55.87
5. measurement	236.4	57.17	237.9	55.86
6. measurement	278.5	57.17	281.1	55.86
7. measurement	321.5	57.13	321.6	55.86
8. measurement	364.4	57.13	364.7	55.85
9. measurement	408.4	57.12	407.3	55.85
10. measurement	451.4	57.13	450.0	55.85
Mean σM [mN/m]		57.16		55.87

Mean (experiments 1 and 2): σmean = 56.52 mN/m

Standard deviation: 0.91 mN/m

Relative standard deviation: 1.6 %

The mean value, multiplied by the calibration factor (F=1.0125) results in:
σ = σmean · F = 57.2 mN/m

Final Result
The surface tension of two aqueous solutions of test item, technical substance, was determined using the OECD harmonized ring method according to the OECD Guideline 115 and European Commission Council Regulation (EC) No 440/2008, Annex, Part A, method A.5.

The solubility of the test item in water is below 1 g/L (178 mg/L in distilled water at 20 °C, flask method).
According to the OECD Guideline and the EC Regulation saturated solutions were prepared and then diluted to 90 % of the saturation concentration. The concentrations of the two solutions were determined by HPLC analyses (results: 86 mg/L for Test solution 1 and 98 mg/L for Test solution 2).

The surface tension of the aqueous solution of test item, technical substance, was: σ  = 57.2 mN/m at 20 °C