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EC number: 700-043-1 | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing conducted betweeen 8 July 2008 and 22 August 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP and in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not effect the quality of the relevant results.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Vapour pressure balance
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure of the test material has been determined to be 1.8 x 10-5 Pa at 25ºC
- Executive summary:
The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The vapour pressure of the test material has been determined to be 1.8 x 10-5 Pa at 25ºC
- Endpoint:
- vapour pressure
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- 1. HYPOTHESIS FOR THE ANALOGUE APPROACH
It is proposed that the structural similarity and properties of the target substance and the structural analogue (sources substance) are sufficiently close for there to be a reasonable expectation of similar effects.
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
Source chemical:
Reaction mass of 3-[3-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)propoxy]-2-hydroxypropyl methacrylate and 1-[3-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)propoxy]-3-hydroxypropan-2-yl methacrylate (EC 700-334-3)
Target chemical:
Reaction mass of 3-[3-(9-butyl-1,1,3,3,5,5,7,7,9,9-decamethylpentasiloxanyl)propoxy]-2-hydroxypropyl 2-methylprop-2-enoate and 1-[3-(9-butyl-1,1,3,3,5,5,7,7,9,9-decamethylpentasiloxanyl)propoxy]-3-hydroxypropan-2-yl 2-methylprop-2-enoate (EC 700-043-1)
3. ANALOGUE APPROACH JUSTIFICATION
It is concluded that the structural similarity, common functional groups and properties of the target substance and the structural analogue (sources substance) are sufficiently close for there to be a reasonable expectation of similar effects.
4. DATA MATRIX
Please see 'Read-across justification to support the REACH registration of OH-mPDMS (EC 700-043-1)' document attached in section 13. - Reason / purpose for cross-reference:
- read-across source
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure of the test material (EC 700-334-3) has been determined to be 1.8 x 10-5 Pa at 25ºC
- Executive summary:
The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The vapour pressure of the test material (EC 700-334-3) has been determined to be 1.8 x 10-5 Pa at 25ºC
Referenceopen allclose all
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for 5 runs gave a summary statistical data as seen below using an unweighted least squares treatment.
Run |
Log10 [Vp(25ºC)] |
1 |
-4.637 |
2 |
-4.749 |
3 |
-4.701 |
4 |
-4.715 |
5 |
-4.964 |
Mean |
-4.753 |
Vapour Pressure |
1.8 x 10-5 Pa |
Description of key information
The vapour pressure of a structurally similar analogue substance (EC 700-334-3) was determined to be 1.8 x 10-5 Pa at 25ºC.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The vapour pressure of the test material has been determined to be 1.8 x 10-5 Pa at 25ºC
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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