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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
other: summary
Rationale for reliability incl. deficiencies:
other: summary

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Prediction of Rodent Carcinogenicity Bioassays from Molecular Structure Using Inductive Logic Programming
Author:
King, R.D. et al.
Year:
1996
Bibliographic source:
Environmental Heatlh Perspectives 104, Supplement 5, 1031-1040, 1996
Reference Type:
publication
Title:
Measuring gene mutation in vivo
Author:
Heddle, J.A. et al.
Year:
1991
Bibliographic source:
Progress in Clinical dn Biological Research 372, 281-289
Reference Type:
publication
Title:
Toward a classibication scheme for degrees of experimental evidence for the carcinogenicity of chemical for animals
Author:
Griesemer, R.A. et al.
Year:
1980
Bibliographic source:
IARC Scientific Publication 27, 259-281
Reference Type:
publication
Title:
A quantitative approach to structure activity correlation in chemical mutagenesis - preliminary studies in the Ames Salmonella/Microsome assay systems
Author:
Johnson, H.L. et al
Year:
1978
Bibliographic source:
DHEW Publ. , ISS: FDA 78-1046, Struct. Correl. Carcinog. Mutagen. 105-111
Reference Type:
publication
Title:
The Salmonella typhimurium/mammalian microsomal assay A report of the U.S. Environmental Protection Agency Gene-Tox Program
Author:
Kier, L.E. et al.
Year:
1986
Bibliographic source:
Mutation Research 168, 69-240
Reference Type:
publication
Title:
The structural basis of the mutagenicity of chemicals in Salmonella typhimurium: The Gene-Tox Data base
Author:
Klopman, G. et al.
Year:
1990
Bibliographic source:
Mutation Research 228, 1-50
Reference Type:
publication
Title:
Genotoxic properties of acrylonitrile
Author:
Lambotte-Vandepaer, M.
Year:
1984
Bibliographic source:
Mutation Research 134, 49-59
Reference Type:
publication
Title:
Learning rules to predict rodent carcinogenicity of non-genotoxic chemicals
Author:
Lee, Y. et al.
Year:
1995
Bibliographic source:
Mutation Research 328, 127-149
Reference Type:
publication
Title:
An Introduction to the Study of Xenobiotic Metabolsim Using Electroanalytical Techniques
Author:
Lunte, S.M. et al.
Year:
1990
Bibliographic source:
Journal of Pharmaceutical Sciences 79, 557-567
Reference Type:
publication
Title:
Mechanism of liver carcinogenesis by certain aminoazo dyes. VIII. Characterization of some unknow dyes found in liver of mice given o-aminoazotoluene
Author:
Matsumoto, M. et al.
Year:
1965
Bibliographic source:
GANN 56, 339-351,

Materials and methods

Type of study / information:
summary
Principles of method if other than guideline:
summary
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(4-aminophenyl)aniline
EC Number:
202-951-9
EC Name:
N-(4-aminophenyl)aniline
Cas Number:
101-54-2
Molecular formula:
C12H12N2
IUPAC Name:
N1-phenylbenzene-1,4-diamine

Results and discussion

Any other information on results incl. tables

summary

Applicant's summary and conclusion